AustralieFrV1, Main, Exploration, bibRecord, 000C73

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

Identifieur interne : 000C73 ( Main/Exploration ); précédent : 000C72; suivant : 000C74

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

Auteurs : Karoline B. Kuchenbaecker ; Lesley Mcguffog ; Daniel Barrowdale ; Andrew Lee ; Penny Soucy ; Sue Healey ; Joe Dennis ; Michael Lush ; Mark Robson ; Amanda B. Spurdle ; Susan J. Ramus ; Nasim Mavaddat ; Mary Beth Terry ; Susan L. Neuhausen ; Ute Hamann ; Melissa Southey ; Esther M. John ; Wendy K. Chung ; Mary B. Daly ; Saundra S. Buys ; David E. Goldgar ; Cecilia M. Dorfling ; Elizabeth J. Van Rensburg ; Yuan Chun Ding ; Bent Ejlertsen ; Anne-Marie Gerdes ; Thomas V. O. Hansen ; Susan Slager ; Emily Hallberg ; Javier Benitez ; Ana Osorio ; Nancy Cohen ; William Lawler ; Jeffrey N. Weitzel ; Paolo Peterlongo ; Valeria Pensotti ; Riccardo Dolcetti ; Monica Barile ; Bernardo Bonanni ; Jacopo Azzollini ; Siranoush Manoukian ; Bernard Peissel ; Paolo Radice ; Antonella Savarese ; Laura Papi ; Giuseppe Giannini ; Florentia Fostira ; Irene Konstantopoulou ; Julian Adlard ; Carole Brewer ; Jackie Cook ; Rosemarie Davidson ; Diana Eccles ; Ros Eeles ; Steve Ellis ; Debra Frost ; Shirley Hodgson ; Louise Izatt ; Fiona Lalloo ; Kai-Ren Ong ; Andrew K. Godwin ; Norbert Arnold ; Bernd Dworniczak ; Christoph Engel ; Andrea Gehrig ; Eric Hahnen ; Jan Hauke ; Karin Kast ; Alfons Meindl ; Dieter Niederacher ; Rita Katharina Schmutzler ; Raymonda Varon-Mateeva ; Shan Wang-Gohrke ; Barbara Wappenschmidt ; Laure Barjhoux ; Marie-Agnès Collonge-Rame ; Camille Elan ; Lisa Golmard ; Emmanuelle Barouk-Simonet ; Fabienne Lesueur ; Sylvie Mazoyer ; Joanna Sokolowska ; Dominique Stoppa-Lyonnet ; Claudine Isaacs ; Kathleen B. M. Claes ; Bruce Poppe ; Miguel De La Hoya ; Vanesa Garcia-Barberan ; Kristiina Aittom Ki ; Heli Nevanlinna ; Margreet G. E. M. Ausems ; J. L. De Lange ; Encarna B. G Mez Garcia ; Frans B. L. Hogervorst ; Carolien M. Kets ; Hanne E. J. Meijers-Heijboer ; Jan C. Oosterwijk ; Matti A. Rookus ; Christi J. Van Asperen ; Ans M. W. Van Den Ouweland ; Helena C. Van Doorn ; Theo A. M. Van Os ; Ava Kwong ; Edith Olah ; Orland Diez ; Joan Brunet ; Conxi Lazaro ; Alex Teulé ; Jacek Gronwald ; Anna Jakubowska ; Katarzyna Kaczmarek ; Jan Lubinski ; Grzegorz Sukiennicki ; Rosa B. Barkardottir ; Jocelyne Chiquette ; Simona Agata ; Marco Montagna ; Manuel R. Teixeira ; Sue Kyung Park ; Curtis Olswold ; Marc Tischkowitz ; Lenka Foretova ; Pragna Gaddam ; Joseph Vijai ; Georg Pfeiler ; Christine Rappaport-Fuerhauser ; Christian F. Singer ; Muy-Kheng M. Tea ; Mark H. Greene ; Jennifer T. Loud ; Gad Rennert ; Evgeny N. Imyanitov ; Peter J. Hulick ; John L. Hays ; Marion Piedmonte ; Gustavo C. Rodriguez ; Julie Martyn ; Gord Glendon ; Anna Marie Mulligan ; Irene L. Andrulis ; Amanda Ewart Toland ; Uffe Birk Jensen ; Torben A. Kruse ; Inge Sokilde Pedersen ; Mads Thomassen ; Maria A. Caligo ; Soo-Hwang Teo ; Raanan Berger ; Eitan Friedman ; Yael Laitman ; Brita Arver ; Ake Borg ; Hans Ehrencrona ; Johanna Rantala ; Olufunmilayo I. Olopade ; Patricia A. Ganz ; Robert L. Nussbaum ; Angela R. Bradbury ; Susan M. Domchek ; Katherine L. Nathanson ; Banu K. Arun ; Paul James ; Beth Y. Karlan ; Jenny Lester ; Jacques Simard ; Paul D. P. Pharoah ; Kenneth Offit ; Fergus J. Couch ; Georgia Chenevix-Trench ; Douglas F. Easton ; Antonis C. Antoniou

Source :

JNCI Journal of the National Cancer Institute [ 0027-8874 ] ; 2017.

RBID : PMC:5408990

Abstract

Background: Genome-wide association studies (GWAS) have identified 94 common single-nucleotide polymorphisms (SNPs) associated with breast cancer (BC) risk and 18 associated with ovarian cancer (OC) risk. Several of these are also associated with risk of BC or OC for women who carry a pathogenic mutation in the high-risk BC and OC genes BRCA1 or BRCA2. The combined effects of these variants on BC or OC risk for BRCA1 and BRCA2 mutation carriers have not yet been assessed while their clinical management could benefit from improved personalized risk estimates.

Methods: We constructed polygenic risk scores (PRS) using BC and OC susceptibility SNPs identified through population-based GWAS: for BC (overall, estrogen receptor [ER]–positive, and ER-negative) and for OC. Using data from 15 252 female BRCA1 and 8211 BRCA2 carriers, the association of each PRS with BC or OC risk was evaluated using a weighted cohort approach, with time to diagnosis as the outcome and estimation of the hazard ratios (HRs) per standard deviation increase in the PRS.

Results: The PRS for ER-negative BC displayed the strongest association with BC risk in BRCA1 carriers (HR = 1.27, 95% confidence interval [CI] = 1.23 to 1.31, P = 8.2×10⁻⁵³). In BRCA2 carriers, the strongest association with BC risk was seen for the overall BC PRS (HR = 1.22, 95% CI = 1.17 to 1.28, P = 7.2×10⁻²⁰). The OC PRS was strongly associated with OC risk for both BRCA1 and BRCA2 carriers. These translate to differences in absolute risks (more than 10% in each case) between the top and bottom deciles of the PRS distribution; for example, the OC risk was 6% by age 80 years for BRCA2 carriers at the 10th percentile of the OC PRS compared with 19% risk for those at the 90th percentile of PRS.

Conclusions: BC and OC PRS are predictive of cancer risk in BRCA1 and BRCA2 carriers. Incorporation of the PRS into risk prediction models has promise to better inform decisions on cancer risk management.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408990

DOI: 10.1093/jnci/djw302
PubMed: 28376175
PubMed Central: 5408990

Affiliations:

Le document en format XML

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<author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name>
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<author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name>
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<author><name sortKey="Lush, Michael" sort="Lush, Michael" uniqKey="Lush M" first="Michael" last="Lush">Michael Lush</name>
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<author><name sortKey="Robson, Mark" sort="Robson, Mark" uniqKey="Robson M" first="Mark" last="Robson">Mark Robson</name>
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<author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name>
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<author><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J." last="Ramus">Susan J. Ramus</name>
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<author><name sortKey="Mavaddat, Nasim" sort="Mavaddat, Nasim" uniqKey="Mavaddat N" first="Nasim" last="Mavaddat">Nasim Mavaddat</name>
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<author><name sortKey="Terry, Mary Beth" sort="Terry, Mary Beth" uniqKey="Terry M" first="Mary Beth" last="Terry">Mary Beth Terry</name>
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<author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L." last="Neuhausen">Susan L. Neuhausen</name>
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<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
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<author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name>
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</affiliation>
</author>
<author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name>
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</affiliation>
</author>
<author><name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K." last="Chung">Wendy K. Chung</name>
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</affiliation>
</author>
<author><name sortKey="Daly, Mary B" sort="Daly, Mary B" uniqKey="Daly M" first="Mary B." last="Daly">Mary B. Daly</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S." last="Buys">Saundra S. Buys</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Goldgar, David E" sort="Goldgar, David E" uniqKey="Goldgar D" first="David E." last="Goldgar">David E. Goldgar</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dorfling, Cecilia M" sort="Dorfling, Cecilia M" uniqKey="Dorfling C" first="Cecilia M." last="Dorfling">Cecilia M. Dorfling</name>
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</affiliation>
</author>
<author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J." last="Van Rensburg">Elizabeth J. Van Rensburg</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Slager, Susan" sort="Slager, Susan" uniqKey="Slager S" first="Susan" last="Slager">Susan Slager</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hallberg, Emily" sort="Hallberg, Emily" uniqKey="Hallberg E" first="Emily" last="Hallberg">Emily Hallberg</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cohen, Nancy" sort="Cohen, Nancy" uniqKey="Cohen N" first="Nancy" last="Cohen">Nancy Cohen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lawler, William" sort="Lawler, William" uniqKey="Lawler W" first="William" last="Lawler">William Lawler</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Weitzel, Jeffrey N" sort="Weitzel, Jeffrey N" uniqKey="Weitzel J" first="Jeffrey N." last="Weitzel">Jeffrey N. Weitzel</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pensotti, Valeria" sort="Pensotti, Valeria" uniqKey="Pensotti V" first="Valeria" last="Pensotti">Valeria Pensotti</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Azzollini, Jacopo" sort="Azzollini, Jacopo" uniqKey="Azzollini J" first="Jacopo" last="Azzollini">Jacopo Azzollini</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Savarese, Antonella" sort="Savarese, Antonella" uniqKey="Savarese A" first="Antonella" last="Savarese">Antonella Savarese</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Konstantopoulou, Irene" sort="Konstantopoulou, Irene" uniqKey="Konstantopoulou I" first="Irene" last="Konstantopoulou">Irene Konstantopoulou</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ellis, Steve" sort="Ellis, Steve" uniqKey="Ellis S" first="Steve" last="Ellis">Steve Ellis</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hodgson, Shirley" sort="Hodgson, Shirley" uniqKey="Hodgson S" first="Shirley" last="Hodgson">Shirley Hodgson</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lalloo, Fiona" sort="Lalloo, Fiona" uniqKey="Lalloo F" first="Fiona" last="Lalloo">Fiona Lalloo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ong, Kai Ren" sort="Ong, Kai Ren" uniqKey="Ong K" first="Kai-Ren" last="Ong">Kai-Ren Ong</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K." last="Godwin">Andrew K. Godwin</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dworniczak, Bernd" sort="Dworniczak, Bernd" uniqKey="Dworniczak B" first="Bernd" last="Dworniczak">Bernd Dworniczak</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hahnen, Eric" sort="Hahnen, Eric" uniqKey="Hahnen E" first="Eric" last="Hahnen">Eric Hahnen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hauke, Jan" sort="Hauke, Jan" uniqKey="Hauke J" first="Jan" last="Hauke">Jan Hauke</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita Katharina" sort="Schmutzler, Rita Katharina" uniqKey="Schmutzler R" first="Rita Katharina" last="Schmutzler">Rita Katharina Schmutzler</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Collonge Rame, Marie Agnes" sort="Collonge Rame, Marie Agnes" uniqKey="Collonge Rame M" first="Marie-Agnès" last="Collonge-Rame">Marie-Agnès Collonge-Rame</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Elan, Camille" sort="Elan, Camille" uniqKey="Elan C" first="Camille" last="Elan">Camille Elan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Golmard, Lisa" sort="Golmard, Lisa" uniqKey="Golmard L" first="Lisa" last="Golmard">Lisa Golmard</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barouk Simonet, Emmanuelle" sort="Barouk Simonet, Emmanuelle" uniqKey="Barouk Simonet E" first="Emmanuelle" last="Barouk-Simonet">Emmanuelle Barouk-Simonet</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lesueur, Fabienne" sort="Lesueur, Fabienne" uniqKey="Lesueur F" first="Fabienne" last="Lesueur">Fabienne Lesueur</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sokolowska, Joanna" sort="Sokolowska, Joanna" uniqKey="Sokolowska J" first="Joanna" last="Sokolowska">Joanna Sokolowska</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Isaacs, Claudine" sort="Isaacs, Claudine" uniqKey="Isaacs C" first="Claudine" last="Isaacs">Claudine Isaacs</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Claes, Kathleen B M" sort="Claes, Kathleen B M" uniqKey="Claes K" first="Kathleen B. M." last="Claes">Kathleen B. M. Claes</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Poppe, Bruce" sort="Poppe, Bruce" uniqKey="Poppe B" first="Bruce" last="Poppe">Bruce Poppe</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Garcia Barberan, Vanesa" sort="Garcia Barberan, Vanesa" uniqKey="Garcia Barberan V" first="Vanesa" last="Garcia-Barberan">Vanesa Garcia-Barberan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ausems, Margreet G E M" sort="Ausems, Margreet G E M" uniqKey="Ausems M" first="Margreet G. E. M." last="Ausems">Margreet G. E. M. Ausems</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De Lange, J L" sort="De Lange, J L" uniqKey="De Lange J" first="J. L." last="De Lange">J. L. De Lange</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="G Mez Garcia, Encarna B" sort="G Mez Garcia, Encarna B" uniqKey="G Mez Garcia E" first="Encarna B." last="G Mez Garcia">Encarna B. G Mez Garcia</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hogervorst, Frans B L" sort="Hogervorst, Frans B L" uniqKey="Hogervorst F" first="Frans B. L." last="Hogervorst">Frans B. L. Hogervorst</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kets, Carolien M" sort="Kets, Carolien M" uniqKey="Kets C" first="Carolien M." last="Kets">Carolien M. Kets</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Meijers Heijboer, Hanne E J" sort="Meijers Heijboer, Hanne E J" uniqKey="Meijers Heijboer H" first="Hanne E. J." last="Meijers-Heijboer">Hanne E. J. Meijers-Heijboer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Oosterwijk, Jan C" sort="Oosterwijk, Jan C" uniqKey="Oosterwijk J" first="Jan C." last="Oosterwijk">Jan C. Oosterwijk</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rookus, Matti A" sort="Rookus, Matti A" uniqKey="Rookus M" first="Matti A." last="Rookus">Matti A. Rookus</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Den Ouweland, Ans M W" sort="Van Den Ouweland, Ans M W" uniqKey="Van Den Ouweland A" first="Ans M. W." last="Van Den Ouweland">Ans M. W. Van Den Ouweland</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Doorn, Helena C" sort="Van Doorn, Helena C" uniqKey="Van Doorn H" first="Helena C." last="Van Doorn">Helena C. Van Doorn</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Os, Theo A M" sort="Van Os, Theo A M" uniqKey="Van Os T" first="Theo A. M." last="Van Os">Theo A. M. Van Os</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kwong, Ava" sort="Kwong, Ava" uniqKey="Kwong A" first="Ava" last="Kwong">Ava Kwong</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brunet, Joan" sort="Brunet, Joan" uniqKey="Brunet J" first="Joan" last="Brunet">Joan Brunet</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Teule, Alex" sort="Teule, Alex" uniqKey="Teule A" first="Alex" last="Teulé">Alex Teulé</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kaczmarek, Katarzyna" sort="Kaczmarek, Katarzyna" uniqKey="Kaczmarek K" first="Katarzyna" last="Kaczmarek">Katarzyna Kaczmarek</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sukiennicki, Grzegorz" sort="Sukiennicki, Grzegorz" uniqKey="Sukiennicki G" first="Grzegorz" last="Sukiennicki">Grzegorz Sukiennicki</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barkardottir, Rosa B" sort="Barkardottir, Rosa B" uniqKey="Barkardottir R" first="Rosa B." last="Barkardottir">Rosa B. Barkardottir</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chiquette, Jocelyne" sort="Chiquette, Jocelyne" uniqKey="Chiquette J" first="Jocelyne" last="Chiquette">Jocelyne Chiquette</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Agata, Simona" sort="Agata, Simona" uniqKey="Agata S" first="Simona" last="Agata">Simona Agata</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R." last="Teixeira">Manuel R. Teixeira</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Park, Sue Kyung" sort="Park, Sue Kyung" uniqKey="Park S" first="Sue Kyung" last="Park">Sue Kyung Park</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olswold, Curtis" sort="Olswold, Curtis" uniqKey="Olswold C" first="Curtis" last="Olswold">Curtis Olswold</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tischkowitz, Marc" sort="Tischkowitz, Marc" uniqKey="Tischkowitz M" first="Marc" last="Tischkowitz">Marc Tischkowitz</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gaddam, Pragna" sort="Gaddam, Pragna" uniqKey="Gaddam P" first="Pragna" last="Gaddam">Pragna Gaddam</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rappaport Fuerhauser, Christine" sort="Rappaport Fuerhauser, Christine" uniqKey="Rappaport Fuerhauser C" first="Christine" last="Rappaport-Fuerhauser">Christine Rappaport-Fuerhauser</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F." last="Singer">Christian F. Singer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tea, Muy Kheng M" sort="Tea, Muy Kheng M" uniqKey="Tea M" first="Muy-Kheng M." last="Tea">Muy-Kheng M. Tea</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H." last="Greene">Mark H. Greene</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Loud, Jennifer T" sort="Loud, Jennifer T" uniqKey="Loud J" first="Jennifer T." last="Loud">Jennifer T. Loud</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rennert, Gad" sort="Rennert, Gad" uniqKey="Rennert G" first="Gad" last="Rennert">Gad Rennert</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Imyanitov, Evgeny N" sort="Imyanitov, Evgeny N" uniqKey="Imyanitov E" first="Evgeny N." last="Imyanitov">Evgeny N. Imyanitov</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hulick, Peter J" sort="Hulick, Peter J" uniqKey="Hulick P" first="Peter J." last="Hulick">Peter J. Hulick</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hays, John L" sort="Hays, John L" uniqKey="Hays J" first="John L." last="Hays">John L. Hays</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rodriguez, Gustavo C" sort="Rodriguez, Gustavo C" uniqKey="Rodriguez G" first="Gustavo C." last="Rodriguez">Gustavo C. Rodriguez</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Martyn, Julie" sort="Martyn, Julie" uniqKey="Martyn J" first="Julie" last="Martyn">Julie Martyn</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kruse, Torben A" sort="Kruse, Torben A" uniqKey="Kruse T" first="Torben A." last="Kruse">Torben A. Kruse</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pedersen, Inge Sokilde" sort="Pedersen, Inge Sokilde" uniqKey="Pedersen I" first="Inge Sokilde" last="Pedersen">Inge Sokilde Pedersen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A." last="Caligo">Maria A. Caligo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Berger, Raanan" sort="Berger, Raanan" uniqKey="Berger R" first="Raanan" last="Berger">Raanan Berger</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Friedman, Eitan" sort="Friedman, Eitan" uniqKey="Friedman E" first="Eitan" last="Friedman">Eitan Friedman</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Laitman, Yael" sort="Laitman, Yael" uniqKey="Laitman Y" first="Yael" last="Laitman">Yael Laitman</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arver, Brita" sort="Arver, Brita" uniqKey="Arver B" first="Brita" last="Arver">Brita Arver</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Borg, Ake" sort="Borg, Ake" uniqKey="Borg A" first="Ake" last="Borg">Ake Borg</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ehrencrona, Hans" sort="Ehrencrona, Hans" uniqKey="Ehrencrona H" first="Hans" last="Ehrencrona">Hans Ehrencrona</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rantala, Johanna" sort="Rantala, Johanna" uniqKey="Rantala J" first="Johanna" last="Rantala">Johanna Rantala</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olopade, Olufunmilayo I" sort="Olopade, Olufunmilayo I" uniqKey="Olopade O" first="Olufunmilayo I." last="Olopade">Olufunmilayo I. Olopade</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ganz, Patricia A" sort="Ganz, Patricia A" uniqKey="Ganz P" first="Patricia A." last="Ganz">Patricia A. Ganz</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nussbaum, Robert L" sort="Nussbaum, Robert L" uniqKey="Nussbaum R" first="Robert L." last="Nussbaum">Robert L. Nussbaum</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bradbury, Angela R" sort="Bradbury, Angela R" uniqKey="Bradbury A" first="Angela R." last="Bradbury">Angela R. Bradbury</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M." last="Domchek">Susan M. Domchek</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L." last="Nathanson">Katherine L. Nathanson</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arun, Banu K" sort="Arun, Banu K" uniqKey="Arun B" first="Banu K." last="Arun">Banu K. Arun</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="James, Paul" sort="James, Paul" uniqKey="James P" first="Paul" last="James">Paul James</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lester, Jenny" sort="Lester, Jenny" uniqKey="Lester J" first="Jenny" last="Lester">Jenny Lester</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">28376175</idno>
<idno type="pmc">5408990</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in <italic>BRCA1</italic>
 and <italic>BRCA2</italic>
 Mutation Carriers</title>
<author><name sortKey="Kuchenbaecker, Karoline B" sort="Kuchenbaecker, Karoline B" uniqKey="Kuchenbaecker K" first="Karoline B." last="Kuchenbaecker">Karoline B. Kuchenbaecker</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barrowdale, Daniel" sort="Barrowdale, Daniel" uniqKey="Barrowdale D" first="Daniel" last="Barrowdale">Daniel Barrowdale</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lee, Andrew" sort="Lee, Andrew" uniqKey="Lee A" first="Andrew" last="Lee">Andrew Lee</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lush, Michael" sort="Lush, Michael" uniqKey="Lush M" first="Michael" last="Lush">Michael Lush</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Robson, Mark" sort="Robson, Mark" uniqKey="Robson M" first="Mark" last="Robson">Mark Robson</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J." last="Ramus">Susan J. Ramus</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mavaddat, Nasim" sort="Mavaddat, Nasim" uniqKey="Mavaddat N" first="Nasim" last="Mavaddat">Nasim Mavaddat</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Terry, Mary Beth" sort="Terry, Mary Beth" uniqKey="Terry M" first="Mary Beth" last="Terry">Mary Beth Terry</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L." last="Neuhausen">Susan L. Neuhausen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K." last="Chung">Wendy K. Chung</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Daly, Mary B" sort="Daly, Mary B" uniqKey="Daly M" first="Mary B." last="Daly">Mary B. Daly</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S." last="Buys">Saundra S. Buys</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Goldgar, David E" sort="Goldgar, David E" uniqKey="Goldgar D" first="David E." last="Goldgar">David E. Goldgar</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dorfling, Cecilia M" sort="Dorfling, Cecilia M" uniqKey="Dorfling C" first="Cecilia M." last="Dorfling">Cecilia M. Dorfling</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J." last="Van Rensburg">Elizabeth J. Van Rensburg</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Slager, Susan" sort="Slager, Susan" uniqKey="Slager S" first="Susan" last="Slager">Susan Slager</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hallberg, Emily" sort="Hallberg, Emily" uniqKey="Hallberg E" first="Emily" last="Hallberg">Emily Hallberg</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cohen, Nancy" sort="Cohen, Nancy" uniqKey="Cohen N" first="Nancy" last="Cohen">Nancy Cohen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lawler, William" sort="Lawler, William" uniqKey="Lawler W" first="William" last="Lawler">William Lawler</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Weitzel, Jeffrey N" sort="Weitzel, Jeffrey N" uniqKey="Weitzel J" first="Jeffrey N." last="Weitzel">Jeffrey N. Weitzel</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pensotti, Valeria" sort="Pensotti, Valeria" uniqKey="Pensotti V" first="Valeria" last="Pensotti">Valeria Pensotti</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Azzollini, Jacopo" sort="Azzollini, Jacopo" uniqKey="Azzollini J" first="Jacopo" last="Azzollini">Jacopo Azzollini</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Savarese, Antonella" sort="Savarese, Antonella" uniqKey="Savarese A" first="Antonella" last="Savarese">Antonella Savarese</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Konstantopoulou, Irene" sort="Konstantopoulou, Irene" uniqKey="Konstantopoulou I" first="Irene" last="Konstantopoulou">Irene Konstantopoulou</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ellis, Steve" sort="Ellis, Steve" uniqKey="Ellis S" first="Steve" last="Ellis">Steve Ellis</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hodgson, Shirley" sort="Hodgson, Shirley" uniqKey="Hodgson S" first="Shirley" last="Hodgson">Shirley Hodgson</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lalloo, Fiona" sort="Lalloo, Fiona" uniqKey="Lalloo F" first="Fiona" last="Lalloo">Fiona Lalloo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ong, Kai Ren" sort="Ong, Kai Ren" uniqKey="Ong K" first="Kai-Ren" last="Ong">Kai-Ren Ong</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K." last="Godwin">Andrew K. Godwin</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dworniczak, Bernd" sort="Dworniczak, Bernd" uniqKey="Dworniczak B" first="Bernd" last="Dworniczak">Bernd Dworniczak</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hahnen, Eric" sort="Hahnen, Eric" uniqKey="Hahnen E" first="Eric" last="Hahnen">Eric Hahnen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hauke, Jan" sort="Hauke, Jan" uniqKey="Hauke J" first="Jan" last="Hauke">Jan Hauke</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita Katharina" sort="Schmutzler, Rita Katharina" uniqKey="Schmutzler R" first="Rita Katharina" last="Schmutzler">Rita Katharina Schmutzler</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Collonge Rame, Marie Agnes" sort="Collonge Rame, Marie Agnes" uniqKey="Collonge Rame M" first="Marie-Agnès" last="Collonge-Rame">Marie-Agnès Collonge-Rame</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Elan, Camille" sort="Elan, Camille" uniqKey="Elan C" first="Camille" last="Elan">Camille Elan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Golmard, Lisa" sort="Golmard, Lisa" uniqKey="Golmard L" first="Lisa" last="Golmard">Lisa Golmard</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barouk Simonet, Emmanuelle" sort="Barouk Simonet, Emmanuelle" uniqKey="Barouk Simonet E" first="Emmanuelle" last="Barouk-Simonet">Emmanuelle Barouk-Simonet</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lesueur, Fabienne" sort="Lesueur, Fabienne" uniqKey="Lesueur F" first="Fabienne" last="Lesueur">Fabienne Lesueur</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sokolowska, Joanna" sort="Sokolowska, Joanna" uniqKey="Sokolowska J" first="Joanna" last="Sokolowska">Joanna Sokolowska</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Isaacs, Claudine" sort="Isaacs, Claudine" uniqKey="Isaacs C" first="Claudine" last="Isaacs">Claudine Isaacs</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Claes, Kathleen B M" sort="Claes, Kathleen B M" uniqKey="Claes K" first="Kathleen B. M." last="Claes">Kathleen B. M. Claes</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Poppe, Bruce" sort="Poppe, Bruce" uniqKey="Poppe B" first="Bruce" last="Poppe">Bruce Poppe</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Garcia Barberan, Vanesa" sort="Garcia Barberan, Vanesa" uniqKey="Garcia Barberan V" first="Vanesa" last="Garcia-Barberan">Vanesa Garcia-Barberan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ausems, Margreet G E M" sort="Ausems, Margreet G E M" uniqKey="Ausems M" first="Margreet G. E. M." last="Ausems">Margreet G. E. M. Ausems</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De Lange, J L" sort="De Lange, J L" uniqKey="De Lange J" first="J. L." last="De Lange">J. L. De Lange</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="G Mez Garcia, Encarna B" sort="G Mez Garcia, Encarna B" uniqKey="G Mez Garcia E" first="Encarna B." last="G Mez Garcia">Encarna B. G Mez Garcia</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hogervorst, Frans B L" sort="Hogervorst, Frans B L" uniqKey="Hogervorst F" first="Frans B. L." last="Hogervorst">Frans B. L. Hogervorst</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kets, Carolien M" sort="Kets, Carolien M" uniqKey="Kets C" first="Carolien M." last="Kets">Carolien M. Kets</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Meijers Heijboer, Hanne E J" sort="Meijers Heijboer, Hanne E J" uniqKey="Meijers Heijboer H" first="Hanne E. J." last="Meijers-Heijboer">Hanne E. J. Meijers-Heijboer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Oosterwijk, Jan C" sort="Oosterwijk, Jan C" uniqKey="Oosterwijk J" first="Jan C." last="Oosterwijk">Jan C. Oosterwijk</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rookus, Matti A" sort="Rookus, Matti A" uniqKey="Rookus M" first="Matti A." last="Rookus">Matti A. Rookus</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Den Ouweland, Ans M W" sort="Van Den Ouweland, Ans M W" uniqKey="Van Den Ouweland A" first="Ans M. W." last="Van Den Ouweland">Ans M. W. Van Den Ouweland</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Doorn, Helena C" sort="Van Doorn, Helena C" uniqKey="Van Doorn H" first="Helena C." last="Van Doorn">Helena C. Van Doorn</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Os, Theo A M" sort="Van Os, Theo A M" uniqKey="Van Os T" first="Theo A. M." last="Van Os">Theo A. M. Van Os</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kwong, Ava" sort="Kwong, Ava" uniqKey="Kwong A" first="Ava" last="Kwong">Ava Kwong</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brunet, Joan" sort="Brunet, Joan" uniqKey="Brunet J" first="Joan" last="Brunet">Joan Brunet</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Teule, Alex" sort="Teule, Alex" uniqKey="Teule A" first="Alex" last="Teulé">Alex Teulé</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kaczmarek, Katarzyna" sort="Kaczmarek, Katarzyna" uniqKey="Kaczmarek K" first="Katarzyna" last="Kaczmarek">Katarzyna Kaczmarek</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sukiennicki, Grzegorz" sort="Sukiennicki, Grzegorz" uniqKey="Sukiennicki G" first="Grzegorz" last="Sukiennicki">Grzegorz Sukiennicki</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barkardottir, Rosa B" sort="Barkardottir, Rosa B" uniqKey="Barkardottir R" first="Rosa B." last="Barkardottir">Rosa B. Barkardottir</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chiquette, Jocelyne" sort="Chiquette, Jocelyne" uniqKey="Chiquette J" first="Jocelyne" last="Chiquette">Jocelyne Chiquette</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Agata, Simona" sort="Agata, Simona" uniqKey="Agata S" first="Simona" last="Agata">Simona Agata</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R." last="Teixeira">Manuel R. Teixeira</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Park, Sue Kyung" sort="Park, Sue Kyung" uniqKey="Park S" first="Sue Kyung" last="Park">Sue Kyung Park</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olswold, Curtis" sort="Olswold, Curtis" uniqKey="Olswold C" first="Curtis" last="Olswold">Curtis Olswold</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tischkowitz, Marc" sort="Tischkowitz, Marc" uniqKey="Tischkowitz M" first="Marc" last="Tischkowitz">Marc Tischkowitz</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gaddam, Pragna" sort="Gaddam, Pragna" uniqKey="Gaddam P" first="Pragna" last="Gaddam">Pragna Gaddam</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rappaport Fuerhauser, Christine" sort="Rappaport Fuerhauser, Christine" uniqKey="Rappaport Fuerhauser C" first="Christine" last="Rappaport-Fuerhauser">Christine Rappaport-Fuerhauser</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F." last="Singer">Christian F. Singer</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tea, Muy Kheng M" sort="Tea, Muy Kheng M" uniqKey="Tea M" first="Muy-Kheng M." last="Tea">Muy-Kheng M. Tea</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H." last="Greene">Mark H. Greene</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Loud, Jennifer T" sort="Loud, Jennifer T" uniqKey="Loud J" first="Jennifer T." last="Loud">Jennifer T. Loud</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rennert, Gad" sort="Rennert, Gad" uniqKey="Rennert G" first="Gad" last="Rennert">Gad Rennert</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Imyanitov, Evgeny N" sort="Imyanitov, Evgeny N" uniqKey="Imyanitov E" first="Evgeny N." last="Imyanitov">Evgeny N. Imyanitov</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hulick, Peter J" sort="Hulick, Peter J" uniqKey="Hulick P" first="Peter J." last="Hulick">Peter J. Hulick</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hays, John L" sort="Hays, John L" uniqKey="Hays J" first="John L." last="Hays">John L. Hays</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rodriguez, Gustavo C" sort="Rodriguez, Gustavo C" uniqKey="Rodriguez G" first="Gustavo C." last="Rodriguez">Gustavo C. Rodriguez</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Martyn, Julie" sort="Martyn, Julie" uniqKey="Martyn J" first="Julie" last="Martyn">Julie Martyn</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kruse, Torben A" sort="Kruse, Torben A" uniqKey="Kruse T" first="Torben A." last="Kruse">Torben A. Kruse</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pedersen, Inge Sokilde" sort="Pedersen, Inge Sokilde" uniqKey="Pedersen I" first="Inge Sokilde" last="Pedersen">Inge Sokilde Pedersen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A." last="Caligo">Maria A. Caligo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Berger, Raanan" sort="Berger, Raanan" uniqKey="Berger R" first="Raanan" last="Berger">Raanan Berger</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Friedman, Eitan" sort="Friedman, Eitan" uniqKey="Friedman E" first="Eitan" last="Friedman">Eitan Friedman</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Laitman, Yael" sort="Laitman, Yael" uniqKey="Laitman Y" first="Yael" last="Laitman">Yael Laitman</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arver, Brita" sort="Arver, Brita" uniqKey="Arver B" first="Brita" last="Arver">Brita Arver</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Borg, Ake" sort="Borg, Ake" uniqKey="Borg A" first="Ake" last="Borg">Ake Borg</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ehrencrona, Hans" sort="Ehrencrona, Hans" uniqKey="Ehrencrona H" first="Hans" last="Ehrencrona">Hans Ehrencrona</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rantala, Johanna" sort="Rantala, Johanna" uniqKey="Rantala J" first="Johanna" last="Rantala">Johanna Rantala</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olopade, Olufunmilayo I" sort="Olopade, Olufunmilayo I" uniqKey="Olopade O" first="Olufunmilayo I." last="Olopade">Olufunmilayo I. Olopade</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ganz, Patricia A" sort="Ganz, Patricia A" uniqKey="Ganz P" first="Patricia A." last="Ganz">Patricia A. Ganz</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nussbaum, Robert L" sort="Nussbaum, Robert L" uniqKey="Nussbaum R" first="Robert L." last="Nussbaum">Robert L. Nussbaum</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bradbury, Angela R" sort="Bradbury, Angela R" uniqKey="Bradbury A" first="Angela R." last="Bradbury">Angela R. Bradbury</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M." last="Domchek">Susan M. Domchek</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L." last="Nathanson">Katherine L. Nathanson</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arun, Banu K" sort="Arun, Banu K" uniqKey="Arun B" first="Banu K." last="Arun">Banu K. Arun</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="James, Paul" sort="James, Paul" uniqKey="James P" first="Paul" last="James">Paul James</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lester, Jenny" sort="Lester, Jenny" uniqKey="Lester J" first="Jenny" last="Lester">Jenny Lester</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name>
<affiliation><nlm:aff id="djw302-aff2"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">JNCI Journal of the National Cancer Institute</title>
<idno type="ISSN">0027-8874</idno>
<idno type="eISSN">1460-2105</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
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</teiHeader>
<front><div type="abstract" xml:lang="en"><p><bold>Background:</bold>
 Genome-wide association studies (GWAS) have identified 94 common single-nucleotide polymorphisms (SNPs) associated with breast cancer (BC) risk and 18 associated with ovarian cancer (OC) risk. Several of these are also associated with risk of BC or OC for women who carry a pathogenic mutation in the high-risk BC and OC genes BRCA1 or BRCA2. The combined effects of these variants on BC or OC risk for <italic>BRCA1</italic>
 and <italic>BRCA2</italic>
 mutation carriers have not yet been assessed while their clinical management could benefit from improved personalized risk estimates.</p>
<p><bold>Methods:</bold>
 We constructed polygenic risk scores (PRS) using BC and OC susceptibility SNPs identified through population-based GWAS: for BC (overall, estrogen receptor [ER]–positive, and ER-negative) and for OC. Using data from 15 252 female <italic>BRCA1</italic>
 and 8211 <italic>BRCA2</italic>
 carriers, the association of each PRS with BC or OC risk was evaluated using a weighted cohort approach, with time to diagnosis as the outcome and estimation of the hazard ratios (HRs) per standard deviation increase in the PRS.</p>
<p><bold>Results:</bold>
 The PRS for ER-negative BC displayed the strongest association with BC risk in <italic>BRCA1</italic>
 carriers (HR = 1.27, 95% confidence interval [CI] = 1.23 to 1.31, <italic>P = </italic>
8.2×10<sup>−53</sup>
). In <italic>BRCA2</italic>
 carriers, the strongest association with BC risk was seen for the overall BC PRS (HR = 1.22, 95% CI = 1.17 to 1.28, <italic>P = </italic>
7.2×10<sup>−20</sup>
). The OC PRS was strongly associated with OC risk for both <italic>BRCA1</italic>
 and <italic>BRCA2</italic>
 carriers. These translate to differences in absolute risks (more than 10% in each case) between the top and bottom deciles of the PRS distribution; for example, the OC risk was 6% by age 80 years for <italic>BRCA2</italic>
 carriers at the 10th percentile of the OC PRS compared with 19% risk for those at the 90th percentile of PRS.</p>
<p><bold>Conclusions:</bold>
 BC and OC PRS are predictive of cancer risk in <italic>BRCA1</italic>
 and <italic>BRCA2</italic>
 carriers. Incorporation of the PRS into risk prediction models has promise to better inform decisions on cancer risk management.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Evans, Dg" uniqKey="Evans D">DG Evans</name>
</author>
<author><name sortKey="Graham, J" uniqKey="Graham J">J Graham</name>
</author>
<author><name sortKey="O Connell, S" uniqKey="O Connell S">S O'Connell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Clark, As" uniqKey="Clark A">AS Clark</name>
</author>
<author><name sortKey="Domchek, Sm" uniqKey="Domchek S">SM. Domchek</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Parker, Wh" uniqKey="Parker W">WH Parker</name>
</author>
<author><name sortKey="Jacoby, V" uniqKey="Jacoby V">V Jacoby</name>
</author>
<author><name sortKey="Shoupe, D" uniqKey="Shoupe D">D Shoupe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rivera, Cm" uniqKey="Rivera C">CM Rivera</name>
</author>
<author><name sortKey="Grossardt, Br" uniqKey="Grossardt B">BR Grossardt</name>
</author>
<author><name sortKey="Rhodes, Dj" uniqKey="Rhodes D">DJ Rhodes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rivera, Cm" uniqKey="Rivera C">CM Rivera</name>
</author>
<author><name sortKey="Grossardt, Br" uniqKey="Grossardt B">BR Grossardt</name>
</author>
<author><name sortKey="Rhodes, Dj" uniqKey="Rhodes D">DJ Rhodes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rocca, Wa" uniqKey="Rocca W">WA Rocca</name>
</author>
<author><name sortKey="Bower, Jh" uniqKey="Bower J">JH Bower</name>
</author>
<author><name sortKey="Maraganore, Dm" uniqKey="Maraganore D">DM Maraganore</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eccles, Dm" uniqKey="Eccles D">DM. Eccles</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Michailidou, K" uniqKey="Michailidou K">K Michailidou</name>
</author>
<author><name sortKey="Hall, P" uniqKey="Hall P">P Hall</name>
</author>
<author><name sortKey="Gonzalez Neira, A" uniqKey="Gonzalez Neira A">A Gonzalez-Neira</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kuchenbaecker, Kb" uniqKey="Kuchenbaecker K">KB Kuchenbaecker</name>
</author>
<author><name sortKey="Ramus, Sj" uniqKey="Ramus S">SJ Ramus</name>
</author>
<author><name sortKey="Tyrer, J" uniqKey="Tyrer J">J Tyrer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Michailidou, K" uniqKey="Michailidou K">K Michailidou</name>
</author>
<author><name sortKey="Beesley, J" uniqKey="Beesley J">J Beesley</name>
</author>
<author><name sortKey="Lindstrom, S" uniqKey="Lindstrom S">S Lindstrom</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kuchenbaecker, Kb" uniqKey="Kuchenbaecker K">KB Kuchenbaecker</name>
</author>
<author><name sortKey="Neuhausen, Sl" uniqKey="Neuhausen S">SL Neuhausen</name>
</author>
<author><name sortKey="Robson, M" uniqKey="Robson M">M Robson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Couch, Fj" uniqKey="Couch F">FJ Couch</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Mcguffog, L" uniqKey="Mcguffog L">L McGuffog</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gaudet, Mm" uniqKey="Gaudet M">MM Gaudet</name>
</author>
<author><name sortKey="Kuchenbaecker, Kb" uniqKey="Kuchenbaecker K">KB Kuchenbaecker</name>
</author>
<author><name sortKey="Vijai, J" uniqKey="Vijai J">J Vijai</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chowdhury, S" uniqKey="Chowdhury S">S Chowdhury</name>
</author>
<author><name sortKey="Dent, T" uniqKey="Dent T">T Dent</name>
</author>
<author><name sortKey="Pashayan, N" uniqKey="Pashayan N">N Pashayan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Antoniou, Ac" uniqKey="Antoniou A">AC Antoniou</name>
</author>
<author><name sortKey="Beesley, J" uniqKey="Beesley J">J Beesley</name>
</author>
<author><name sortKey="Mcguffog, L" uniqKey="Mcguffog L">L McGuffog</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Milne, Rl" uniqKey="Milne R">RL Milne</name>
</author>
<author><name sortKey="Antoniou, Ac" uniqKey="Antoniou A">AC. Antoniou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Antoniou, Ac" uniqKey="Antoniou A">AC Antoniou</name>
</author>
<author><name sortKey="Beesley, J" uniqKey="Beesley J">J Beesley</name>
</author>
<author><name sortKey="Mcguffog, L" uniqKey="Mcguffog L">L McGuffog</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Couch, Fj" uniqKey="Couch F">FJ Couch</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Mcguffog, L" uniqKey="Mcguffog L">L McGuffog</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mavaddat, N" uniqKey="Mavaddat N">N Mavaddat</name>
</author>
<author><name sortKey="Peock, S" uniqKey="Peock S">S Peock</name>
</author>
<author><name sortKey="Frost, D" uniqKey="Frost D">D Frost</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mavaddat, N" uniqKey="Mavaddat N">N Mavaddat</name>
</author>
<author><name sortKey="Pharoah, Pd" uniqKey="Pharoah P">PD Pharoah</name>
</author>
<author><name sortKey="Michailidou, K" uniqKey="Michailidou K">K Michailidou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lin, Wy" uniqKey="Lin W">WY Lin</name>
</author>
<author><name sortKey="Camp, Nj" uniqKey="Camp N">NJ Camp</name>
</author>
<author><name sortKey="Ghoussaini, M" uniqKey="Ghoussaini M">M Ghoussaini</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ghoussaini, M" uniqKey="Ghoussaini M">M Ghoussaini</name>
</author>
<author><name sortKey="Edwards, Sl" uniqKey="Edwards S">SL Edwards</name>
</author>
<author><name sortKey="Michailidou, K" uniqKey="Michailidou K">K Michailidou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bojesen, Se" uniqKey="Bojesen S">SE Bojesen</name>
</author>
<author><name sortKey="Pooley, Ka" uniqKey="Pooley K">KA Pooley</name>
</author>
<author><name sortKey="Johnatty, Se" uniqKey="Johnatty S">SE Johnatty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="French, Jd" uniqKey="French J">JD French</name>
</author>
<author><name sortKey="Ghoussaini, M" uniqKey="Ghoussaini M">M Ghoussaini</name>
</author>
<author><name sortKey="Edwards, Sl" uniqKey="Edwards S">SL Edwards</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Meyer, Kb" uniqKey="Meyer K">KB Meyer</name>
</author>
<author><name sortKey="O Reilly, M" uniqKey="O Reilly M">M O'Reilly</name>
</author>
<author><name sortKey="Michailidou, K" uniqKey="Michailidou K">K Michailidou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dunning, Am" uniqKey="Dunning A">AM Dunning</name>
</author>
<author><name sortKey="Michailidou, K" uniqKey="Michailidou K">K Michailidou</name>
</author>
<author><name sortKey="Kuchenbaecker, Kb" uniqKey="Kuchenbaecker K">KB Kuchenbaecker</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Southey, Mc" uniqKey="Southey M">MC Southey</name>
</author>
<author><name sortKey="Goldgar, De" uniqKey="Goldgar D">DE Goldgar</name>
</author>
<author><name sortKey="Winqvist, R" uniqKey="Winqvist R">R Winqvist</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Antoniou, Ac" uniqKey="Antoniou A">AC Antoniou</name>
</author>
<author><name sortKey="Goldgar, De" uniqKey="Goldgar D">DE Goldgar</name>
</author>
<author><name sortKey="Andrieu, N" uniqKey="Andrieu N">N Andrieu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Harrell, Fe" uniqKey="Harrell F">FE Harrell</name>
</author>
<author><name sortKey="Califf, Rm" uniqKey="Califf R">RM Califf</name>
</author>
<author><name sortKey="Pryor, Db" uniqKey="Pryor D">DB Pryor</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Amin Al Olama, A" uniqKey="Amin Al Olama A">A Amin Al Olama</name>
</author>
<author><name sortKey="Benlloch, S" uniqKey="Benlloch S">S Benlloch</name>
</author>
<author><name sortKey="Antoniou, Ac" uniqKey="Antoniou A">AC Antoniou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Aulchenko, Ys" uniqKey="Aulchenko Y">YS Aulchenko</name>
</author>
<author><name sortKey="Ripke, S" uniqKey="Ripke S">S Ripke</name>
</author>
<author><name sortKey="Isaacs, A" uniqKey="Isaacs A">A Isaacs</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Lakhani, Sr" uniqKey="Lakhani S">SR Lakhani</name>
</author>
<author><name sortKey="Jacquemier, J" uniqKey="Jacquemier J">J Jacquemier</name>
</author>
<author><name sortKey="Sloane, Jp" uniqKey="Sloane J">JP Sloane</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mavaddat, N" uniqKey="Mavaddat N">N Mavaddat</name>
</author>
<author><name sortKey="Barrowdale, D" uniqKey="Barrowdale D">D Barrowdale</name>
</author>
<author><name sortKey="Andrulis, Il" uniqKey="Andrulis I">IL Andrulis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Symons, Mj" uniqKey="Symons M">MJ Symons</name>
</author>
<author><name sortKey="Moore, Dt" uniqKey="Moore D">DT. Moore</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Husing, A" uniqKey="Husing A">A Husing</name>
</author>
<author><name sortKey="Canzian, F" uniqKey="Canzian F">F Canzian</name>
</author>
<author><name sortKey="Beckmann, L" uniqKey="Beckmann L">L Beckmann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rocca, Wa" uniqKey="Rocca W">WA Rocca</name>
</author>
<author><name sortKey="Grossardt, Br" uniqKey="Grossardt B">BR Grossardt</name>
</author>
<author><name sortKey="De Andrade, M" uniqKey="De Andrade M">M de Andrade</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rebbeck, Tr" uniqKey="Rebbeck T">TR Rebbeck</name>
</author>
<author><name sortKey="Kauff, Nd" uniqKey="Kauff N">ND Kauff</name>
</author>
<author><name sortKey="Domchek, Sm" uniqKey="Domchek S">SM. Domchek</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Antoniou, Ac" uniqKey="Antoniou A">AC Antoniou</name>
</author>
<author><name sortKey="Cunningham, Ap" uniqKey="Cunningham A">AP Cunningham</name>
</author>
<author><name sortKey="Peto, J" uniqKey="Peto J">J Peto</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tung, N" uniqKey="Tung N">N Tung</name>
</author>
<author><name sortKey="Domchek, Sm" uniqKey="Domchek S">SM Domchek</name>
</author>
<author><name sortKey="Stadler, Z" uniqKey="Stadler Z">Z Stadler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anderson, K" uniqKey="Anderson K">K Anderson</name>
</author>
<author><name sortKey="Jacobson, Js" uniqKey="Jacobson J">JS Jacobson</name>
</author>
<author><name sortKey="Heitjan, Df" uniqKey="Heitjan D">DF Heitjan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Evans, Dg" uniqKey="Evans D">DG Evans</name>
</author>
<author><name sortKey="Lalloo, F" uniqKey="Lalloo F">F Lalloo</name>
</author>
<author><name sortKey="Ashcroft, L" uniqKey="Ashcroft L">L Ashcroft</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name>
<name sortKey="Agata, Simona" sort="Agata, Simona" uniqKey="Agata S" first="Simona" last="Agata">Simona Agata</name>
<name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name>
<name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name>
<name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name>
<name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name>
<name sortKey="Arun, Banu K" sort="Arun, Banu K" uniqKey="Arun B" first="Banu K." last="Arun">Banu K. Arun</name>
<name sortKey="Arver, Brita" sort="Arver, Brita" uniqKey="Arver B" first="Brita" last="Arver">Brita Arver</name>
<name sortKey="Ausems, Margreet G E M" sort="Ausems, Margreet G E M" uniqKey="Ausems M" first="Margreet G. E. M." last="Ausems">Margreet G. E. M. Ausems</name>
<name sortKey="Azzollini, Jacopo" sort="Azzollini, Jacopo" uniqKey="Azzollini J" first="Jacopo" last="Azzollini">Jacopo Azzollini</name>
<name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name>
<name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name>
<name sortKey="Barkardottir, Rosa B" sort="Barkardottir, Rosa B" uniqKey="Barkardottir R" first="Rosa B." last="Barkardottir">Rosa B. Barkardottir</name>
<name sortKey="Barouk Simonet, Emmanuelle" sort="Barouk Simonet, Emmanuelle" uniqKey="Barouk Simonet E" first="Emmanuelle" last="Barouk-Simonet">Emmanuelle Barouk-Simonet</name>
<name sortKey="Barrowdale, Daniel" sort="Barrowdale, Daniel" uniqKey="Barrowdale D" first="Daniel" last="Barrowdale">Daniel Barrowdale</name>
<name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name>
<name sortKey="Berger, Raanan" sort="Berger, Raanan" uniqKey="Berger R" first="Raanan" last="Berger">Raanan Berger</name>
<name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name>
<name sortKey="Borg, Ake" sort="Borg, Ake" uniqKey="Borg A" first="Ake" last="Borg">Ake Borg</name>
<name sortKey="Bradbury, Angela R" sort="Bradbury, Angela R" uniqKey="Bradbury A" first="Angela R." last="Bradbury">Angela R. Bradbury</name>
<name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name>
<name sortKey="Brunet, Joan" sort="Brunet, Joan" uniqKey="Brunet J" first="Joan" last="Brunet">Joan Brunet</name>
<name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S." last="Buys">Saundra S. Buys</name>
<name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A." last="Caligo">Maria A. Caligo</name>
<name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<name sortKey="Chiquette, Jocelyne" sort="Chiquette, Jocelyne" uniqKey="Chiquette J" first="Jocelyne" last="Chiquette">Jocelyne Chiquette</name>
<name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K." last="Chung">Wendy K. Chung</name>
<name sortKey="Claes, Kathleen B M" sort="Claes, Kathleen B M" uniqKey="Claes K" first="Kathleen B. M." last="Claes">Kathleen B. M. Claes</name>
<name sortKey="Cohen, Nancy" sort="Cohen, Nancy" uniqKey="Cohen N" first="Nancy" last="Cohen">Nancy Cohen</name>
<name sortKey="Collonge Rame, Marie Agnes" sort="Collonge Rame, Marie Agnes" uniqKey="Collonge Rame M" first="Marie-Agnès" last="Collonge-Rame">Marie-Agnès Collonge-Rame</name>
<name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name>
<name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name>
<name sortKey="Daly, Mary B" sort="Daly, Mary B" uniqKey="Daly M" first="Mary B." last="Daly">Mary B. Daly</name>
<name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name>
<name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name>
<name sortKey="De Lange, J L" sort="De Lange, J L" uniqKey="De Lange J" first="J. L." last="De Lange">J. L. De Lange</name>
<name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name>
<name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name>
<name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name>
<name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name>
<name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M." last="Domchek">Susan M. Domchek</name>
<name sortKey="Dorfling, Cecilia M" sort="Dorfling, Cecilia M" uniqKey="Dorfling C" first="Cecilia M." last="Dorfling">Cecilia M. Dorfling</name>
<name sortKey="Dworniczak, Bernd" sort="Dworniczak, Bernd" uniqKey="Dworniczak B" first="Bernd" last="Dworniczak">Bernd Dworniczak</name>
<name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name>
<name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name>
<name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name>
<name sortKey="Ehrencrona, Hans" sort="Ehrencrona, Hans" uniqKey="Ehrencrona H" first="Hans" last="Ehrencrona">Hans Ehrencrona</name>
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<name sortKey="Golmard, Lisa" sort="Golmard, Lisa" uniqKey="Golmard L" first="Lisa" last="Golmard">Lisa Golmard</name>
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<name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name>
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<name sortKey="Hallberg, Emily" sort="Hallberg, Emily" uniqKey="Hallberg E" first="Emily" last="Hallberg">Emily Hallberg</name>
<name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name>
<name sortKey="Hauke, Jan" sort="Hauke, Jan" uniqKey="Hauke J" first="Jan" last="Hauke">Jan Hauke</name>
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<name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name>
<name sortKey="Hodgson, Shirley" sort="Hodgson, Shirley" uniqKey="Hodgson S" first="Shirley" last="Hodgson">Shirley Hodgson</name>
<name sortKey="Hogervorst, Frans B L" sort="Hogervorst, Frans B L" uniqKey="Hogervorst F" first="Frans B. L." last="Hogervorst">Frans B. L. Hogervorst</name>
<name sortKey="Hulick, Peter J" sort="Hulick, Peter J" uniqKey="Hulick P" first="Peter J." last="Hulick">Peter J. Hulick</name>
<name sortKey="Imyanitov, Evgeny N" sort="Imyanitov, Evgeny N" uniqKey="Imyanitov E" first="Evgeny N." last="Imyanitov">Evgeny N. Imyanitov</name>
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<name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name>
<name sortKey="Kaczmarek, Katarzyna" sort="Kaczmarek, Katarzyna" uniqKey="Kaczmarek K" first="Katarzyna" last="Kaczmarek">Katarzyna Kaczmarek</name>
<name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name>
<name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name>
<name sortKey="Kets, Carolien M" sort="Kets, Carolien M" uniqKey="Kets C" first="Carolien M." last="Kets">Carolien M. Kets</name>
<name sortKey="Konstantopoulou, Irene" sort="Konstantopoulou, Irene" uniqKey="Konstantopoulou I" first="Irene" last="Konstantopoulou">Irene Konstantopoulou</name>
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<name sortKey="Van Den Ouweland, Ans M W" sort="Van Den Ouweland, Ans M W" uniqKey="Van Den Ouweland A" first="Ans M. W." last="Van Den Ouweland">Ans M. W. Van Den Ouweland</name>
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<name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name>
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</tree>
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</record>

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   |texte=   Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers
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Serveur d'exploration sur les relations entre la France et l'Australie

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

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	Serveur d'exploration sur les relations entre la France et l'Australie
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